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Solution and Solid-phase Reagents

Aurora offers a line of solution and solid-phase reagents for use in chemical coupling reactions.

Pre-activated acetylation reagent for amines and alcohols. Applications include the preparation of amide libraries as well as amine derivatization for GC analysis.

CAS Number:  N/A
Base Silica Description: 50 micron particle size, 60A pore size
Substitution: 0.30 – 0.60 mmole/g resin, as determined by formation of N-isopropylacetamide
Appearance: off-white powder
Storage: Store in a cool place and protect from moisture.

Pre-activated benzoylation reagent for amines and alcohols. Applications include the preparation of amide libraries as well as amine derivatization for GC and HPLC analysis.

CAS Number:  N/A
Base Silica Description: 50 micron particle size, 60A pore size
Substitution: 0.30 – 0.60 mmole/g resin, as determined by formation of N-isopropylbenzamide
Appearance: off-white powder
Storage: Store in a cool place and protect from moisture.

Phosphorylating agent.

CAS Number:  819-43-2 Boiling Point: 110-113 °C @ 6 mm Hg
Chemical Formula: C8H18ClO3P 31P NMR consistent with  structure
Molecular Weight: 228.65 g/mole Solubility: methanol
Purity: 98% Appearance: clear liquid
Storage: 2-8 C, protect from light and moisture

Coupling agent for amide and sulfonamide bond formation.

CAS Number:  N/A Boiling Point: N/A
Chemical Formula: C9H9N3O3 LC-MS N/A
Molecular Weight: 207.19 g/mole Solubility: N/A
Purity: 98% Appearance: off-white fluffy powder
Storage: Cool, dry, well ventilated place, away from heat and electrostatic charge

Coupling agent.

CAS Number:  50907-17-7 Boiling Point: n/a
Chemical Formula: C7H5N3O3 LC-MS n/a
Molecular Weight: 179.13 g/mole Solubility: n/a
Purity: 98% Appearance: fine peach-colored powder
Storage: Cool, dry, well ventilated place, away from heat and electrostatic charge

Silica gel bound HOBt for the synthesis of amides, sulfonamides and carbamate protected amines.

CAS Number:  1312158-81-1
Base Silica Description: 50 micron particle size, 60A pore size
Substitution: 0.30 – 0.60 mmole/g resin, as determined by formation of N-isopropylbenzamide
Appearance: off-white powder
Storage: Store in a cool place and protect from moisture.

 

CAS Number:  16024-55-8 Boiling Point: 71-76 °C @ 6 mm Hg
Chemical Formula: C5H9ClO3 LC-MS
Molecular Weight: 152.58 g/mole Solubility:
Purity: 95% Appearance: clear liquid
Storage: 2-8 C, protect from light and moisture

 

CAS Number:  16024-56-9 Boiling Point: 245-250 °C
Chemical Formula: C5H10O4 LC-MS
Molecular Weight: 134.13 g/mole Solubility:
Purity: 98% Appearance: clear liquid
Storage: 2-8 C, protect from light and moisture